关键词:

肝移植 , 输血 , 血栓弹力图

Abstract:

Objective The prediction of blood use during liver transplantation was analyzed bythe relevant indexes of thromboelastography （TEG） and conventional coagulation tests （CCTs） before liver transplantation. Methods Twenty-two patients undergoing liver transplantation from July 2016 to December 2021, the Hepatobiliary Department of the Eighth Medical Center of the People's Liberation Army General Hospital were monitored for TEG and CCTs before operation， and the data were statistically analyzed. Results Blood transfusion was mainlyused during and after liver transplantation. The ratio of suspended red blood cells to frozen plasma to platelets was 1 ：2.31 ：0.13. The number of red blood cells and plasma transfusion during liver transplantation had linear relationship with R，K， ANGLE， MA， PT， INR， APTT， HB and HCT. The number of platelets transfused had a linear relationship with K，ANGLE， PT， INR， APTT and HCT. Preoperative R value， MA， HB and HCT could predict whether a large amount ofblood was used during operation. TEG had certain correlation with CCTs. Compared with the group with MELD score ＞10 and the group with MELD score ≤ 10， the amount of red blood cells used during operation was significantly increased （P＜0.05）， the K value was significantly prolonged （P＜0.05）， the ANGLE angle was significantly decreased（P＜0.05），and the MA value was significantly decreased （P ＜ 0.01）， with statistical differences. Conclusion The combination of TEG and CCTs to monitor the coagulation function of liver transplant patients before operation has certain guiding significance for the blood use during liver transplantation， especially for the prediction of large amount of blood use during liver transplantation. 

Key words:

Liver transplantation；Blood transfusion； Thrombelastography ,