关键词: 移植 , 肾 , 老年

Abstract:

Objective To summarize the experience of clinical treatment in elderly patients after renal transplantation，and to evaluate its curative effect. Methods Forty-six cases of renaltransplantation patientsover the age of 60 admitted to the Third People's Hospital of Shanxi Datong from September 1998 to June 2010 were retrospectively analyzed. From 1998 to 2005，patients were treated with triple drug use（20 cases），prednisone（Pre），cyclosporineA（CsA）and mycophenolate mofetil（MMF）. From 2005 to 2010，patients were treated with triple drug use（26 cases），methylprednisolone（MP），tacrolimus（FK506）and MMF. Results In these 46 cases of geriatricrenal transplant patients，postoperative complications were happened in 12 cases（26.1%），pulmonary infection in 4 cases，urinary tract infection in 4 cases，upper respiratory tract infection in 3 cases，herpes virus infection in 1 case， acute rejection（AR）in 9 cases（19.6%），and 3 cases（6.5%）died of heart failure. Transplantation kidney and the patients were alive in the other 43 cases. During the follow-up，3 cases got chronic allograft nephropathy，2 of whom had experienced AR. Conclusions The patients over 60 years old can receive kidney transplantation successfully. The main reasons leading to death were cardiac complication and infection. The indication of recipients and using of immunosuppressive agent properly are the keys to prolong the survival time.

Key words: Transplantation, Kidney , Geriatric patient