Objective To explore the treatment value of transjugular introhepatic portosystemic shunts （TIPS）as the bridge to liver transplantation for the patients with acute variceal bleeding and decompensate liver cirrhosis. Methods The clinical data of the 21 patients with acute variceal bleeding who received TIPS at The First People’s Hospital of Foshan between January 2015 and December 2019 were analyzed retrospectively. Results Among the 21 patients，19 cases were male，2 cases were female. The median age was 52 （41 ～ 67）years. There were 15 cases in the TIPS group，6 cases in the TIPS plus liver transplantation group. Cover stent was used in all patients. TIPS treatment decreased the portal vein pressure significantly（7 cmH2O to 24 cmH2O） （1 cmH2O ＝ 0.098 kPa）. The median follow up time was 37.5 months for the TIPS group，and 27 months for the TIPS plus LT group respectively. There were 4 cases with hepatocellular carcinoma in the pure TIPS group ，one died of tumor recurrence and acute variceal bleeding recurrence in the TIPS group. Two cases had tumor recurrence. One case had new occurrence of hepatocellular carcinoma after TIPS treatment in the TIPS group. The patients lived wellin the TIPS plus liver transplantation group. Conclusion TIPS was with significant treatment value for the patients with acute variceal bleeding of decompensate liver cirrhosis，and TIPS also deserved as a bridge treatment for liver transplantation.