关键词:

肾移植 , 围术期 , 用血

Abstract:

Objective To analyze the changes of perioperative blood transfusion and laboratory test results of kidney transplantation patients，and to provide the basis for clinical judgment of perioperativeblood transfusion strategy of kidney transplantation patients. Methods The perioperative blood transfusion of 330 patients with kidney transplantation in 8th Medical Center of PLA General Hospital from 2016 to 2022 was retrospectively analyzed. The difference of preoperative routine blood test indexes between 237 patients without blood transfusion and 93 patients with blood transfusion during perioperative period of kidney transplantation were analyzed and compared. The immune rejection and nosocomial infection after kidney transplantation between perioperative blood transfusion patients and without blood transfusion patients were analyzed and compared. Results The proportion of perioperative blood transfusion in 330 kidney transplantation patients was 28.18%（93/330）. There were statistically significant differences in intraoperative blood loss，operation duration，preoperative hemoglobin， hematocrit，prothrombin activity and other indexes between patients without blood transfusion and with blood transfusionduring the perioperative period of kidney transplantation（P ＜ 0.05）. The incidence of nosocomial infection was 4.55%（15/330）in 330 patients with kidney transplantation，and 9.68%（9/93）in 93 patients with perioperative blood transfusion，which was significantly higher than that in 237 patients without blood transfusion（2.53%，6/237）（P ＜ 0.05）. The incidence of immune rejection in 330 patients with kidney transplantation was 9.39%（31/330），including 12.9%（12/93）in patients with perioperative blood transfusion was，and 8.02%（19/237）in patients without blood transfusion. There was no significant difference between the two groups（P ＞ 0.05）. Conclusion It is necessary to strengthen the monitoring of perioperative coagulation function of kidney transplantation patients，actively preoperative anemia treatment and coagulation level regulation，minimize intraoperative blood loss and shorten operation duration，rationally utilize blood resources，improve the transfusion efficacy of kidney transplantation patients are necessary to improve the prognosis of patients. 

Key words:

Kidney transplantation, Perioperative, Blood transfusion