Objective To investigate the effect of vascular interventional therapy on transplanted renal arterial stenosis(TRAS). Methods The patients with concurrent TRAS among 513 patients with renal transplantation were retrospectively enrolled. The changes of creatinine,blood pressure and hemodynamic index of transplanted renal hemography in patients 1 week,1 month,3 months,and 6 months after treatment were compared. Results Of the 513 patients with kidney transplantation,9 experienced concurrent TRAS,with an incidence rate of 1.75%. The 9 patients were treated with vascular interventional treatment,8 patients received simple balloon expansion and 1 patient was implanted with vascular stents after balloon expansion. In patients with cystic dilation,3 cases recurred within 2 months of surgery,with a secondary stenosis rate of 33.3%,and the secondary cystic dilation was successful. All patients were followed up for 6 months,and one patient died of lung infection 4 months after vascular intervention therapy. Blood creatinine in pre-treatment patients was(142.3±59.6)μmol/L,and were (133.5±57.2)μmol/L,(131.8±35.6)μmol/L,(127.0±29.9)μmol/L,(125.7±37.1)μmol/L at 1 week,1 month, 3 months,6 months after treatment,respectively. Although there is no statistical difference,there is a downward trend after treatment. Pre-treatment systolic pressure was(149.7±19.3)mmHg(1 mmHg = 0.133 kPa),the value were(131.3±4.1)mmHg,(136.2±7.9)mmHg,(128.5±6.6)mmHg,(127.1±3.6)mmHg at 1 week,1 month,3 months,6 months after treatment. Systolic pressure was significantly reduced compared with pre-treatment level. The Pre-treatment transplanted renal aortic peak systolic velocity(PSV)was(297.2±105.3)cm/s,the velocity were (171±56.3)cm/s,(185.8±64.8)cm/s,(197.5±69.1)cm/s,(178.8±75.4)cm/s at 1 week,1 month,3 months, 6 months after treatment, There are statistical differences compared with pre-treatment. The interfolate arterial PSV, interfolate artery resistance index were similar at 1 week,1 month,3 months,6 months after treatment compared to preoperative levels. Conclusion Vascular interventional therapy is effective in improving the transplanted kidney function of TRAS patients.