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Analysis of the efficacy of vascular interventional therapy for transplanted renal artery stenosis  
Li Shuxin, Zhao Yongheng, Chen Wenzhong, Hu Wei, Zhou Yunchong, Song Yonglin, Ma Yinrui, Sun Xun.
2020, 8 (2): 106-109. DOI: 10.3969/j.issn.2095-5332.2020.02.007
Abstract234)      PDF (2529KB)(109)      
Objective To investigate the effect of vascular interventional therapy on transplanted renal arterial stenosis(TRAS). Methods The patients with concurrent TRAS among 513 patients with renal transplantation were retrospectively enrolled. The changes of creatinine,blood pressure and hemodynamic index of transplanted renal hemography in patients 1 week,1 month,3 months,and 6 months after treatment were compared. Results Of the 513 patients with kidney transplantation,9 experienced concurrent TRAS,with an incidence rate of 1.75%. The 9 patients were treated with vascular interventional treatment,8 patients received simple balloon expansion and 1 patient was implanted with vascular stents after balloon expansion. In patients with cystic dilation,3 cases recurred within 2 months of surgery,with a secondary stenosis rate of 33.3%,and the secondary cystic dilation was successful. All patients were followed up for 6 months,and one patient died of lung infection 4 months after vascular intervention therapy. Blood creatinine in pre-treatment patients was(142.3±59.6)μmol/L,and were (133.5±57.2)μmol/L,(131.8±35.6)μmol/L,(127.0±29.9)μmol/L,(125.7±37.1)μmol/L at 1 week,1 month, 3 months,6 months after treatment,respectively. Although there is no statistical difference,there is a downward trend after treatment. Pre-treatment systolic pressure was(149.7±19.3)mmHg(1 mmHg = 0.133 kPa),the value were(131.3±4.1)mmHg,(136.2±7.9)mmHg,(128.5±6.6)mmHg,(127.1±3.6)mmHg at 1 week,1 month,3 months,6 months after treatment. Systolic pressure was significantly reduced compared with pre-treatment level. The Pre-treatment transplanted renal aortic peak systolic velocity(PSV)was(297.2±105.3)cm/s,the velocity were (171±56.3)cm/s,(185.8±64.8)cm/s,(197.5±69.1)cm/s,(178.8±75.4)cm/s at 1 week,1 month,3 months, 6 months after treatment, There are statistical differences compared with pre-treatment. The interfolate arterial PSV, interfolate artery resistance index were similar at 1 week,1 month,3 months,6 months after treatment compared to preoperative levels. Conclusion Vascular interventional therapy is effective in improving the transplanted kidney function of TRAS patients.
2024, 12 (1): 93-96. DOI: 10.3969/j.issn.2095-5332.2024.01.020
Abstract81)      PDF (673KB)(24)      
2022, 10 (2): 146-146. DOI: 10.3969/j.issn.2095-5332.2022.02.010
Abstract312)      PDF (684KB)(612)      
2015, 3 (2): 74-78.
Abstract49)      PDF (785KB)(347)      
2024, 12 (5): 433-438. DOI: 10.3969/j.issn.2095-5332.2024.05.012
Abstract49)      PDF (1089KB)(21)      
The effect of the holistic care on the quality of life in patients with postoperative infection after kidney transplantation
Ding Mei.
2019, 7 (2): 109-112. DOI: 10.3969/j.issn.2095-5332.2019.02.005
Abstract158)      PDF (2450KB)(111)      

Objective To explore the effect of the holistic care on the quality of life assessment systemin patients with postoperative infection after kidney transplantation. Methods The clinical data of 92 patients with infection after renal transplantation in our hospital from January 2017 to December 2017, were analysed retrospectively. The patients were divided into nursing group(observation group)and routine nursing(controlgroup),according to different nursing plans,each group has 46 patients. The nursing quality were compared between the two groups,mainly on the scores of the nursing quality,survival quality score,anxiety score,compliance evaluation,physical comfort,environmental comfort ratings,and patient satisfaction. Results The comprehensive nursing quality(education,nursing attitude,nursing skills,ward management)in the observation group were significantly higher than that in the control group,and the difference were statistically significant(χ2 = 14.286,P = 0.003 ;χ2 = 16.331,P = 0.003 ;χ2 = 19.247,P = 0.002 ;χ2 = 18.295,P = 0.003). The survival quality score in the observation group was significantly higher than that in thecontrol group,and the difference was statistically significant(t = 4.672,P = 0.002). Anxiety scores in the observation group were significantly lower than that in the control group,and the difference was statistically significant(t = -4.855,P = 0.003).The compliance score,physiological comfort score and environmental comfortscore in the observation group were significantly higher than those in the control group,and the difference werestatistically significant(t = -19.218,P = 0.002 ;t = -14.821,P = 0.003 ;t = -16.115,P = 0.002).Nursing satisfaction in observation group was significantly higher than that in control group,and the difference was statistically significant(χ2 = 4.873,P = 0.001)Conclusion “The holistic care”intervention could reduce the psychologicalburden of patients and their families as well as relieve the pain on the body,mind and spirit in all aspects. This method could also improve the quality of patients' lives along with the quality of nursing work. It has important guidingsignificance for clinical management of infection after renal transplantation and related nursing work.

2022, 10 (4): 301-308. DOI: 10.3969/j.issn.2095-5332.2022.04.003
Abstract304)      PDF (741KB)(934)      
华文洁, 王梓涛, 陈静瑜
2024, 12 (1): 66-70. DOI: 10.3969/j.issn.2095-5332.2024.01.015
Abstract94)      PDF (704KB)(13)      
Research hotspots and trends of artificial intelligence in organ transplantation
Lin Xiaohong , Jia Yingtian , Liu Hongxia , Ding Zhenshan .
2025, 13 (6): 489-496. DOI: 10.3969/j.issn.2095-5332.2025.06.002
Abstract15)      PDF (2735KB)(10)      

Objective To analyze the research hotspots and development trends of artificial intelligencein the field of organ transplantation. Methods Literatures on the application of artificial intelligence inthe field of organ transplantation from January 2004 to June 2024 were retrieved from the Web of ScienceCore Collection and China National Knowledge Infrastructure database. CiteSpace 6.2.R6 software was used for visual analysis. Results A total of 728 relevant literatures were retrieved559 English literatures and 143 Chinese literatures were included after screening. The number of literatures published in the early stage was small,while the number of literatures published in recent years has increased significantly. The country with the largest number of articles was the United States,followed by China. The top three institutions in terms of foreignpublications were Mayo Clinic,University of Toronto and Harvard University. Zhejiang University,Peking UnionMedical College and the First Affiliated Hospital of Sun Yat-sen University were the most active institutions in China. The authors who have published the most articles in English were Cheungpasitporn Wisit and Thongprayoon Charat,and the author who has published the most articles in Chinese was Ren Bin. The main high-frequency keywords in English were machine learning,survival,artificial intelligence,liver transplantation,kidney transplantation,mortality,risk,model,outcome and deep learning. The main high-frequency keywords in Chinese were machine learning liver transplantation kidney transplantation deep learning artificial intelligence hepatocellular carcinoma,radiomics,liver cancer,prognosis and tacrolimus. The first emergent keywords in English were artificial neural networks,data mining and survival analysis,and the most recent were predictive model and kidney transplant. The first emergent keywords in Chinese were neural networks,cyclosporine A,and blood concentration,and the most recent were deep learning and machine learning. Conclusion The application of artificial intelligence in thefield of organ transplantation is increasing significantly. The use of machine learning and deep learning to construct prediction models and to analyze the survival of various organ transplantation patients is a current research hotspots. In the future,exchanges and cooperation between countries and disciplines can be strengthened to promote the study and application of advanced AI technologies,so as to further promote the development of this field. 

2018, 6 (4): 243-250. DOI: 10.3969/j.issn.2095-5332.2018.04.001
Abstract124)      PDF (679KB)(70)      
2018, 6 (4): 307-. DOI: 10.3969/j.issn.2095-5332.2018.04.012
Abstract69)      PDF (654KB)(27)      
Investigation on factors affecting medication adherence after renal transplantation and the effect of nursing intervention
Li Wen, Hua Yan.
2020, 8 (2): 110-114. DOI: 10.3969/j.issn.2095-5332.2020.02.008
Abstract151)      PDF (2846KB)(83)      
Objective To investigate factors affecting medication adherence of patients who take immunosuppressive agents after kidney transplantation and to evaluate the effectiveness of specific nursing interventions. Methods A questionnaire survey was conducted in patients and nurses to find out the factors that affect medication compliance,and targeted nursing intervention methods were proposed. A total of 100 renal transplant patients in 2017 were collected and divided into intervention group and control group. The intervention group were subdivided into 4 groups,3 received single intervention seperately,the comprehensive intervention group received all of the intervention. The effect were evaluated with modified Morisky Medication Adherence Evaluation Scale,and the results were just good or not good. Chi-square test was used to analyze difference between groups. Results Factors that affect medication adherence were:① insufficient knowledge about the importance of taking medicine under order. ② Problem concerning medicine management. ③ Inadequate management of patients after discharge. Rate of good adherence in all intervention groups was 84%,that is higher than 60% in the control group(P < 0.05). The rate of good adherence in comprehensive intervention group was 91.3% which was significantly higher than the control group (P < 0.05). Comparison between other groups didn’t show any statistical difference. Conclusion Our studyexplored several important factors that affect medication adherence of patients who take immunosuppressive agents after kidney transplantation. Interventions focusing on these factors improve medication adherence. Comprehensive intervention was more effective than applying single intervention method
2022, 10 (3): 193-195. DOI: 10.3969/j.issn.2095-5332.2022.03.001
Abstract75)      PDF (906KB)(74)      
2022, 10 (6): 503-506. DOI: DOI:10.3969/j.issn.2095-5332.2022.06.005
Abstract75)      PDF (982KB)(4)      
2023, 11 (3): 202-205. DOI: DOI :10.3969/j.issn.2095-5332.2023.03.003
Abstract87)      PDF (682KB)(4)      
2025, 13 (1): 1-6. DOI: 10.3969/j.issn.2095-5332.2025.01.001
Abstract59)      PDF (1006KB)(58)      
2025, 13 (1): 67-72. DOI: 10.3969/j.issn.2095-5332.2025.01.016
Abstract74)      PDF (790KB)(27)      
2020, 8 (6): 433-435. DOI: 10.3969/j.issn.2095-5332.2020.06.005
Abstract86)      PDF (1799KB)(103)      
Analysis of the causes of transplanted kidney loss in recipients within 1 year after DCD donor kidney transplantation( 50 clinical reports attached)
Li Chao, Bai Hongwei, Shi Bingyi, Li Gang, Xie Junjie, Xie Xiaomei, Zhang Shanshan, Liu Yanzhong.
2020, 8 (6): 446-450. DOI: 10.3969/j.issn.2095-5332.2020.06.008
Abstract175)      PDF (3081KB)(88)      

Objective To investigate the causes of kidney graft loss in early stage (within 1 yearafter surgery) in recipients with donation after cardiac death (DCD) kidney transplantation. Methods A retrospective analysis of the clinical data of 50 recipients with early kidney graft loss after DCD donor kidneytransplantation was performed. Results 50 recipients lost transplanted kidneys. The causes of kidney loss included19 rejections(38.0%),17 deaths(34.0%)with normal transplanted kidney function,5 vascular complications of transplanted kidneys(10.0%),4 cases ofcarbapenem-resistant Klebsiella infection(8%),4 cases of primary non-functioning kidney(8.0%),and 1 case of recurrence of primary kidney disease(2.0%). The main reason for the lossof the transplanted kidney in the recipient within 1 year after the DCD donor kidney transplantation is rejection,and the secondary cause is the death of the recipient with normal renal function,complications of the transplanted kidney,primary non-functional kidney,and drug-resistant infection. Recurrence of the primary disease of the diseased kidney was rare. Conclusion Summarizing the reasons for early graft loss after DCD donor kidney transplantationis to provides reference for organ transplant physicians to strengthen targeted prevention and treatment. Ultimately,it may increase the 1-year survival of DCD donor kidney transplantation and reduce the dissatisfaction or medicaldispute caused by patients and their families.

The role of CD4+ T lymphocyte ATP assay in predicting infections after liver transplantation
WANG Kai, GAO Wei, ZHU Zhi-jun, SUN Li-ying, SUN Xiao-ye, QU Wei, SHEN Zhong-yang.
2013, 1 (1): 44-46.
Abstract98)      PDF (1736KB)(89)      
Objective To investigate the relationship between the CD4+T lymphocytes ATP level inperipheral blood and infections after liver transplantation(LT). Methods Total 142 samples were collected from101 patients' peripheral blood post-LT. CD4+T lymphocytes ATP value was analyzed by ImmuKnow immune cellfunction assay kits. According to the occurrence of infection and immune responses conditions,the patients post-LTwere divided into different groups and then the relationship between the level of CD4+T cells ATP and infection wasanalyzed. Results According to the clinical state,the patients were divided into infection group and non-infectiongroup. CD4+T lymphocytes ATP value was significantly different between the two groups(P = 0.001),which were236.0(41.0~512.0)μg/L and 371.5(9.0~1000.0)μg/L respectively. On the other hand,the patients post-LT weredivided into low immune response group,normal immune response group and high immune response according to the ATP levels of CD4+T lymphocytes in peripheral blood. The infection rates were 25.0%,13.6% and 0 in these groupsrespectively,which had significant statistic difference among three groups(P = 0.003). Conclusion The ATP value of CD4+T lymphocyte in peripheral blood was significantly correlated with occurrence of infection post-LT whichwould be helpful to conduct clinical therapy.