实用器官移植电子杂志

实用器官移植电子杂志 ›› 2023, Vol. 11 ›› Issue (1): 10-13.DOI: 10.3969/j.issn.2095-5332.2023.01.003

• 论著 • 上一篇    下一篇

76 例器官捐献供体全身感染情况的流行病学分析

钟仕利 1 ，伍正彬 1 ，陈春燕 1 ，杜欣 2 ，牟继双 2 ，杨倩 2    

  1. 1. 陆军军医大学大坪医院重症医学科，重庆 400042 ；

    2. 陆军军医大学大坪医院 OPO 办公室，重庆 400042

  • 出版日期:2023-01-20 发布日期:2023-03-29
  • 基金资助:

    重庆市医学重点专科建设项目〔委办（2020 -186）〕 

Epidemiological analysis of systemic infection in 76 organ donors 

Zhong Shili1 ， Wu Zhengbin1 ，Chen Chunyan1 ，Du Xin2 ， Mou Jishuang2 ，Yang Qian2 .   

  1. 1. Department of Critical Care Medicine，Third Affiliated Hospital of PLA Military Medical University （Daping Hospital），Chongqing 400042，China.

    2. OPO Office， Daping Hospital，Army Medical University，Chongqing 400042，China.

  • Online:2023-01-20 Published:2023-03-29

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摘要：

目的 对器官捐献供体的全身感染情况进行分析，为控制供体感染提供更多临床证据。方法 回顾性分析陆军军医大学大坪医院重症医学科 2014 年 1 月至 2021 年 12 月期间维护的 76 例器官捐献供体，其中包括 32 例脑死亡患者和 44 例心死亡患者，收集供体年龄、性别、发病原因、感染部位、痰培养及药敏试验结果、中心静脉导管血培养及药敏试验结果、外周血培养及药敏结果、尿培养及药敏试验结果等临床资料。结果 76 例器官捐献供体中肺部是最常见的感染部位，分析感染病原菌得出其中革兰氏阴性杆菌占总比 30.3%，革兰氏阳性球菌占总比 14.4%，真菌占总比 5.3%，多重耐药菌共 6 株，占总比 15.8%。结论 感染并不是器官捐献禁忌证，在发现供体有感染或怀疑感染时应及早启动抗感染治疗方案，积极留取各部位标本送检，以便筛选感染部位及确定感染病原菌，及时目标性抗感染治疗。

关键词:

器官捐献 , 供体 , 感染

Abstract:

Objective To analyze the systemic infection of organ donation donors， and to provide more clinical evidence for the control of donor infection. Methods 76 cases of organ donation were completed in theDepartment of Critical Care Medicine of the Third Affiliated Hospital of PLA Military Medical University （Daping Hospital）from January 2017 to December 2021，including 32 cases of donation after brain death （DBD） and 44 cases of donation after circulatory death （DCD）. Clinical data of donor age， sex， cause of disease， infection site， sputum culture and drug sensitivity test results， central venous catheter blood culture and drug sensitivity test results， peripheral blood culture and drug sensitivity test results， urine culture and drug sensitivity test results were collected. Results Lung infection was the most common site in 76 organ donors. Gram negative bacteria accounted for 30.3%， gram positive cocci accounted for 14.4% ，fungi accounted for 5.3%，and 6 strains of multidrug-resistant bacteria accounted for 15.8% of the total cases. Conclusion Infection is not a contraindicated for organ donation. When the donor is found to have infection or suspected infection， anti-infective treatment should be initiated as soon as possible. Samples from various sites should be actively collected for examination to screen the infected sites and determine the pathogenic bacteria，and to guide timely target anti-infective treatment. 

Key words:

Organ donation； , Donors； , Infection

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