Abstract:

Objective To investigate the clinical features of kidney transplantation of small pediatric donors into pediatric recipients. Methods A retrospective analysis of clinical data and follow-up status in50 kidney transplants from small pediatric donors into pediatric recipients was performed. Results Based on their transplantation type，the patients were divided into two groups: the single kidney transplantation （SKT, 37 cases）group and the en bloc kidney transplantation（EBKT，13 cases）group. In SKT group，postoperative complications included vascular thrombosis in 1 patient（2.7%），ureteral stenosis in 1 patient（2.7%），delayed graft function（DGF）in 17 patients（45.9%）and acute rejection（AR）in 4 patients （10.8%）. In EBKT group，postoperative complications included vascular thrombosis in 4 patients（30.8%），urine leak in 2 patients（15.4%），DGF in 2 patients（15.4%）and acute rejection in 2 patients（15.4%）. At last follow-up，patients survival rates were 100% in both groups，whereas grafts survival rates were 94.6% in SKT group 3-31 months and 76.9% in EBKT group（4-44 months）. At last follow-up，the mean serum creatinine in SKT and EBKT groupwere（67.9±23.1）μmol/L and（56.2±18.7）μmol/L，respectively. Conclusions Favorable outcomes can be obtained from transplantation from small pediatric donors. The use of this donor population for pediatric recipients should be encouraged.