关键词:

结核性脓肿 , 肾移植 , 延误诊断

Abstract:

Objective There is an increased risk of tuberculosis infection after kidney transplantation， but tuberculous abscess after kidney transplantation is rarely reported. This article will discuss the clinical diagnosis andtreatment of tuberculous abscess after kidney transplantation and the causes of delayed diagnosis. Methods A total of 2173 patients who underwent deceased donor kidney transplantation in the Second Xiangya Hospital of Central South University from January 2015 to January 2023 were analyzed retrospectively. A total of 40 patients were diagnosed with tuberculosis post renal transplant， including 3 patients with tuberculous abscess. The clinical manifestations， diagnosis，treatment and prognosis of patients with tuberculous abscess were observed and analyzed. Results The mean time from kidney transplantation to the onset of the disease in 3 patients with tuberculous abscess was 15 months. The mean time from the onset to the start of antituberculosis therapy was 35.7 d and the mean time from onset to etiological diagnosis was 86.3 d. The anti-tuberculous and drainage treatment were effective. And serum creatinine had no significant change compared with that before treatment. Conclusion For patients with abscess after kidney transplantation， it is necessary to keep alert of the possibility of tuberculous infection. Especially for patients whose symptoms do not improve after conventional treatment，it is necessary to collect samples for etiological and molecular biological examination as soon as possible to confirm the diagnosis. For this kind of patients， the prognosis is favorable after regular anti-tuberculosis and drainage therapy at the same time. 

Key words:

 , Tuberculous abscess； Kidney transplantation； Delayed diagnosis