关键词: 糖尿病肾病 , 肾移植

Abstract:

Objective To investigate the prognosis and management strategies of renal transplant recipientswith end-stage diabetic nephropathy. Methods The clinical data of 276 recipients of deceased donor kidneytransplantation after the death of citizens in our hospital from January 2015 to January 2018 were retrospectively analyzed. Twenty patients with diabetic nephropathy were defined as the experimental group and 256 patients withnon-diabetic nephropathy were defined as the control group. The delayed recovery of renal function（DGF），infection，rejection and the survival of transplant recipients and kidneys during perioperative period of kidney transplantation were compared between the two groups. Results The incidence of DGF，infection and rejection in the experimentalgroup was higher than that in the control group during the perioperative period，but there was no significant differencebetween the two groups. In addition，there was no significant difference in the survival rate of transplant recipients and kidneys in the two groups at 1，2 and 3 years after transplantation. Conclusion End-stage diabetic nephropathyrecipients are likely to suffer from infection，DGF and rejection during perioperative period. Perioperative managementand long-term scientific and comprehensive follow-up should be strengthened. There is no difference in 3 years survival rate between diabetic nephropathy recipients and non-diabetic nephropathy recipients.

Key words: Diabetic nephropathy, Kidney transplantation