Abstract:

Objective To investigate the clinical effect of ex vivo ureteroscopic holmium laser lithotripsy combined with Lifeport perfusion on donation after citizen's death（DCD） donor kidney with calculi. Methods The calculi in DCD donor kidneys, were treated with ureteroscopic holmium laser lithotripsy, including 5 cases of right kidney stones and 5 cases of left kidney stones . Crushed stone surgery throughout the kidney placed in the ice kidney preservation solution，low pressure, low temperature washing, holmium laser power was 1.2 ~ 1.6 J / 15 ~ 20 Hz. After lithotripsy, all kidneys were preserved by Lifeport mechanical perfusion , and then renal transplantation was performed. The donor's renal ureter was routinely matched to the recipient's bladder and the 6 F D-J tube was left. Results One patient had delayed recovery of renal function. All patients underwented cystoscopy at 4 weeks after operation for pulling out D-J tube. Patients were followed up for 3 to 22 months. No hydronephrosis was found in the color Doppler ultrasonography. Two patients encountered stone recurrence in graft kidney after one year of transplatation with stable kidney function. Conclusion Ex vivo ureteroscopic holmium laser lithotrpsy combined with Lifeport perfusion treatment of calculi in DCD donor kidneys is an effective method to expand the donor kidney pool, and the clinical curative effect is good.