关键词:

超声衰减指数 ； 脂肪肝 ； 供肝评估 ,

Abstract:

Objective To explore the application value of the ultrasonic attenuation coefficient（ATT）combined with elastography to quantitatively evaluate the steatosis degree of donor liver. Methods We collected 27 cases of brain death donors. Ultrasound examination was performed for all donor livers before operation. Measurement parameters include young's modulus（E），shear wave velocity（Vs），index of fibrosis（F index），index of activity（A index）and ultrasonic ATT for donor liver. During the operation，liver tissue was taken for pathological examination to observe whether the liver tissue had steatosis change. According to the pathological results，the donors were divided into the fatty liver group and the non-fatty liver group，the difference of ultrasound parameters between the two groups was compare. Results In this study，there were 27 brain-death donors，7 were pathologically diagnosed with fatty liver and 20 without. ATT in the fatty liver group（0.54±0.06）was significantly higher than that in the non-fatty liver group（0.45±0.07）（P ＜ 0.05），and there was no significant difference in other parameters （V，A，Vs，F）between the two groups（P ＞ 0.05）. Moreover，ATT was significantly positively correlated with whether the donor liver is fatty liver or not（r ＝ 0.54，P ＜ 0.05），while other parameters have no significantly correlation with the pathological diagnosis of fatty liver（P ＞ 0.05）. ROC curve was performed to analyze thediagnostic efficiency of ATT，the area under the curve，sensitivity and specificity of ATT in diagnosing steatotic change of donor liver were 0.868，85.7% and 85.0%，respectively. Conclusion ATT can quantitatively evaluatewhether the donor liver has steatosis or not，it has certain clinical value. 

Key words:

Ultrasonic attenuation coefficient, Fatty liver disease, Donor liver from brain death