Objective To analyze the relationship between the energy metabolism of donor liver before and post recanalization of blood vessels and the ischemic injury of bile duct injury after liver transplantation. Methods The data of patients who received liver transplantation in Tianjin First Center Hospital between March 2014 and August 2015 were analysed retrospectively. The patients who were satisfied with the standard were enrolled，and samples were taken before recanalization of portal vein，before recanalization of hepatic artery and 1 hour after recanalization of hepatic artery. Patients were followed for one year，patients enrolled were divided into ischemic-type biliary lesions（ITBL）group and non-ischemic-type biliary lesions（NITBL）group according to results of cholangiography. ATP，ADP and AMP at three timepoints in two groups were compared. Results There was no significance difference in energy metabolism showed by indices such as ATP，ADP and AMP， between ITBL group and NITBL group before recanalization of portal vein, before recanalization of hepatic artery and1 hour after recanalization of hepatic artery（P ＞ 0.05）. Conclusion There was no relationship between energy metabolism of donor liver and the occurrence of ITBL post liver transplantation.

目的 探讨肝移植手术过程中血管开放前后供肝能量代谢是否与肝移植术后缺血性胆管损伤 的发生具有相关性。方法 回顾性分析 2014 年 3 月 - 2015 年 8 月天津市第一中心医院 150 例接受原位肝脏 移植手术的患者资料。将满足入组标准的患者于肝移植过程中分别于门静脉开放前、肝动脉开放前及肝动 脉开放后 1 小时取肝组织标本，然后将入组患者随访至 1 年。根据胆道造影结果将其分为缺血性胆道损伤 组（ITBL 组）和非缺血性胆道损伤组（NITBL 组），将两组患者 3 个时间段的 ATP、ADP 及 AMP 定量检测 结果进行分析统计并得出结果。结果 ITBL 组与 NITBL 组在门静脉开放前、肝动脉开放前、肝动脉开放后 3 个时间段的能量代谢相关指标，即 ATP、ADP 及 AMP 含量差异均无统计学意义（P ＞ 0.05）。结论 供肝 组织能量代谢情况与肝移植术后 ITBL 的发生并无相关性。