Retrospective analysis of 25 cases of pediatric liver transplantation

doi:10.3969/j.issn.2095-5332.2021.04.009

Practical Journal of Organ Transplantation(Electronic Version) ›› 2021, Vol. 9 ›› Issue (4): 299-303.DOI: 10.3969/j.issn.2095-5332.2021.04.009

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Retrospective analysis of 25 cases of pediatric liver transplantation

Li Tianxiang，Sun Yandong，Li Zhiqiang，Liu Dan，Teng Dahong，Wu Bin，Liu Hong，Li Xinqiang，Cai Jinzhen.

OrganTransplantation Center，Affiliated Hospital of Qingdao university，Qingdao 266000，China.

Online:2021-07-20 Published:2023-04-12

25 例儿童肝移植病例回顾及分析

李天翔，孙延东，李志强，刘单，滕大洪，吴斌，刘虹，李新强，蔡金贞

青岛大学附属医院器官移植中心，山东青岛 266000

Abstract

Abstract:

Objective To explore the influence of surgical methods and perioperative management onclinical outcomes of pediatric liver transplantation in a single center. Methods The clinical data of 25 pediatric liver transplantation patients from January 2016 to January 2021 in organ transplantation center of the Affiliated Hospital of Qingdao University were included to observe the general results，postoperative surgical complications and prognosis. Results Among the 25 cases, 3 cases died within 2 months after operation，2 cases experienced portal vein stenosis and 1 case experience delayed recovery of liver function. The postoperative 2-month survival rate was 86.4%，and the 1-year survival rate was 86.4%. Up to now，the graft function of 22 patients recovered well， and the immunosuppressant concentration remained in a stable range. Conclusion The success rate and survival rate of pediatric liver transplantation in our center are acceptable，and it is still necessary to strengthen perioperative management in order to achieve better long-term survival results.

Key words:

Liver transplantation , Children , Split liver transplantation , Domino livertransplantation, Prognosis

摘要：

目的探讨单中心儿童肝移植手术方式、围术期管理对患者临床结局的影响。方法纳入青岛大学附属医院器官移植中心自 2016 年 1 月— 2021 年 1 月 25 例儿童肝移植患者临床资料，观察患者的一般结果、术后外科并发症以及预后。结果本组 25 例患儿中，3 例患儿术后 2 个月内死亡，门静脉狭窄 2 例，肝功能延迟恢复 1 例，术后 2 个月生存率为 86.4%，1 年生存率为 86.4%，随访至今，22 例存活患儿的移植物均恢复良好，免疫抑制剂药物浓度维持在稳定区间。结论本中心儿童肝移植的手术成功率及术后生存率尚可，仍需加强围术期管理，以期获得更好的远期存活效果。

关键词:

肝移植 , 儿童 , 劈离式肝移植 , 多米诺肝移植 , 预后

Li Tianxiang, Sun Yandong, Li Zhiqiang, Liu Dan, Teng Dahong, Wu Bin, Liu Hong, Li Xinqiang, Cai Jinzhen..

Retrospective analysis of 25 cases of pediatric liver transplantation

[J]. Practical Journal of Organ Transplantation(Electronic Version), 2021, 9(4): 299-303.

李天翔, 孙延东, 李志强, 刘单, 滕大洪, 吴斌, 刘虹, 李新强, 蔡金贞.

25 例儿童肝移植病例回顾及分析

[J]. 实用器官移植电子杂志, 2021, 9(4): 299-303.

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Retrospective analysis of 25 cases of pediatric liver transplantation

25 例儿童肝移植病例回顾及分析

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