Abstract:

Objective To explore the research status and hotspots of postoperative infection in lungtransplantation in the past decade. Methods The literature related to lung transplantation infection from 2014 to 2023 was searched based on the Web of Science core collection database，and CiteSpace6.2.R2 software was used to analyze the network of authors，countries，publishing institutions，as well as keyword co-occurrence，clustering，and emergence. Results A total of 1457 articles were included. The year of 2022 was the year with the highest number of publications. Husain Shahid’s team published the most papers. The United States was the country with the most papers，and the University of Toronto was the institution with the most papers. The keyword co-occurrence showed that the hotpots mainly focus on infection prevention and management，immune response and infection，assessment，treatment and research. Sixteen major sections were generated by keyword clustering with the value of the clustering module Q ＝ 0.76 and the average contour value of clustering S ＝ 0.89，and 26 keywords with citation explosion were obtained by keyword emergence. Conclusion At present，the research on lung transplantation infection is popular，and the research in Europe and the United States is in a leading position. The research hotspots mainly focuson the management of postoperative fungal and viral infections，immunity and rejection，and rapid diagnosis. Accurate assessment and rapid differentiation of immune rejection and infection，imaging-assisted diagnosis of infection，and management of viral infection in lung transplantation recipients are the research frontiers of lung transplantation infection. 

Key words:

Lung transplantation, Infection, CiteSpace, Visualization analysis

摘要：

目的 探讨近十年肺移植术后感染的研究现状及研究热点。 方法 检索 Web of Science 核心合集数据库中 2014—2023 年的肺移植术后感染相关文献，应用 CiteSpace6.2.R2 软件对检索到的文献进行作者、国家、发文机构网络分析以及关键词共现、聚类和突现等分析。 结果 共纳入 1 457 篇文献 ；2022 年是发文量最高的年份 ；Husain Shahid 团队发表文献最多，美国是发文量最多的国家，多伦多大学是发文量最多的机构 ；关键词共现显示研究热点主要集中在感染的预防与管理，免疫反应与感染，评估、治疗与研究等方面 ；关键词聚类生成 16 大板块，研究聚类模块值 Q ＝ 0.76，聚类平均轮廓值 S ＝ 0.89 ；关键词突现获得 26 个引用爆发的关键词。 结论 目前关于肺移植感染相关研究热度较高，欧美国家的研究处于领先地位。研究热点主要聚焦在术后真菌与病毒感染管理、免疫与排斥反应和快速诊断等方面。准确评估和快速区分免疫排斥与感染，影像学辅助感染诊断和做好肺移植受者病毒感染的管理是肺移植感染的研究前沿。

关键词: 肺移植 , 感染 , CiteSpace , 可视化分析