Abstract:

Objective To explore the characteristics of perioperative complications in renal transplant recipients with diabetic end-stage renal disease. Methods Sixty-three patients with diabetic end-stage renal disease transplanted in the renal transplantation department of the First Affiliated Hospital of Xi'an Jiaotong University during January 2015 to January 2022 were selected as the experimental group （the diabetic group）， and 61 recipients receiving thekidney on the other side of the same donor were selected as the control group （the non-diabetic group）. Preoperative clinical data and perioperative complications of renal transplantation were compared between the two groups. Statistical analysis was performed using the SPSS 22.0 software. Results The study found significant difference in age， body mass index， time of onset， bladder residual urine， incidence of medium-to-severe coronary artery stenosis and iliac artery lesions （P＜0.05）.In the diabetic group， patients had a higher incidence of delayed graft function， cardiovascular and cerebrovascularcomplications， poor incision healing， and urine leakage， resulting in significantly longer graft function recovery time and hospitalization time （P ＜ 0.05）. Conclusion In the perioperative period of renal transplantation， the incidence of complications of patients with diabetic end-stage renal disease are higher，these complications can affect the recovery oftransplanted kidney function in the short term，but most of the complications are controllable， and a relatively satisfactorytransplantation effect can still be achieved after active treatment. 

Key words:

Kidney transplantation； , Diabetic end-stage kidney disease； , Perioperative period； , Complications

摘要：

目的 探讨原发病为糖尿病终末期肾病的肾移植受者围术期并发症的发病特点及对移植效果的影响。方法 选取 2015 年 1 月— 2022 年 1 月期间于西安交通大学第一附属医院肾移植科接受肾移植手术的 63 例糖尿病终末期肾病患者作为实验组（即糖尿病组），接受同一供体另一侧肾脏的受者 61 例作为对照组（即非糖尿病组）。比较两组患者的术前临床资料及肾移植围术期并发症等数据。应用 SPSS 22.0 软件进行统计学分析。结果 研究发现糖尿病组与对照组患者在年龄、体重指数、发病时间、膀胱残余尿、冠状动脉中 - 重度狭窄发生率、髂动脉病变等数据相比，以上差异均有统计学意义（P ＜ 0.05）。糖尿病组患者在肾移植围术期移植肾功能延迟恢复（delayed graft function，DGF）、心脑血管并发症、切口愈合不良、漏尿等并发症发生率更高，进而导致移植肾功能恢复时间、住院时间更长，以上差异有统计学意义（P ＜ 0.05）。 结论 在肾移植围术期，糖尿病终末期肾病患者的并发症发病率更高，但大部分并发症是可控的，短期内可影响移植肾功能恢复，经过积极治疗仍可取得比较满意的移植效果。

关键词:

肾移植 , 糖尿病终末期肾病 , 围术期 , 并发症