Abstract:

Objective To explore and summarize the therapeutic effect of cytomegalovirus（CMV）infection with valganciclovir prophylaxis after lung transplantation. Methods A retrospective analysis of 11 cases of lung transplantation in patients with clinical data in Henan Provincial People's Hospital from September 2015 to April 2017. We summarized the experience of treatment with valganciclovir prophylaxis after lung transplantation CMV infection. Results 11 cases of patients after lung transplantation were started oral valganciclovir oral 900 mg/d， 3 months of therapy，including 1 cases of postoperative 37 days due to liver and kidney failure，bronchial anastomotic fistula infection 1 cases death loss prevention were lost. The remaining 9 cases had not yet found signs of giant cell virus infection. Effect of CMV infection in lung transplantation. Conclusion Prevention valganciclovir 3 months after the standard is exact and it helps to reduce postoperative complications.

摘要：

目的 探讨总结使用缬更昔洛韦预防肺移植术后巨细胞病毒（CMV）感染的疗效。方法 回顾 性分析河南省人民医院 2015 年 9 月-2017 年 4 月 11 例肺移植患者的临床资料，总结使用缬更昔洛韦预防 肺移植术后 CMV 感染的治疗体会。结果 11 例肺移植患者术后均开始采用每日口服缬更昔洛韦 900 mg， 口服 3 个月疗法，其中 1 例术后 37 天因肝肾功能衰竭，支气管吻合口瘘感染死亡失防。1 例外院复查失访； 其余 9 例随访至今仍未发现 CMV 感染迹象。结论 缬更昔洛韦 3 个月标准预防肺移植术后 CMV 感染的疗 效确切，有助于降低术后并发症。