Abstract:

Objective To investigate the risk factors of recurrent ventricular fibrillation in patients with silicosis and hyperthyroidism during and after lung transplantation, for its effective intervention and reducing the risk of operation. Methods Methods The clinical data of one patient with silicosis and hyperthyroidism who underwent recurrent ventricular fibrillation during and after lung transplantation was analyzed retrospectively, and the relevant literatures were reviewed. Results Male 69 years old, he needed lung transplantation because of respiratory failure with silicosis, but diagnosed with hyperthyroidism preoperatively. After standardized treatment in department of endocrinology, lung transplantation was performed after hyperthyroidism was well controlled. However, recurrent ventricular fibrillation occurred during and after the operation and successfully discharged after active rescue. Postoperative follow-up was conducted for three months，the patient recovered well. Conclusion For lung transplant patients with hyperthyroidism, we must actively intervene and regularly review the thyroid function and cardiac involvement. However, there will still be fatal arrhythmias during and after the operation.

Objective To investigate the risk factors of recurrent ventricular fibrillation in patients with silicosis and hyperthyroidism during and after lung transplantation, for its effective intervention and reducing the risk of operation. Methods Methods The clinical data of one patient with silicosis and hyperthyroidism who underwent recurrent ventricular fibrillation during and after lung transplantation was analyzed retrospectively, and the relevant literatures were reviewed. Results Male 69 years old, he needed lung transplantation because of respiratory failure with silicosis, but diagnosed with hyperthyroidism preoperatively. After standardized treatment in department of endocrinology, lung transplantation was performed after hyperthyroidism was well controlled. However, recurrent ventricular fibrillation occurred during and after the operation and successfully discharged after active rescue. Postoperative follow-up was conducted for three months，the patient recovered well. Conclusion For lung transplant patients with hyperthyroidism, we must actively intervene and regularly review the thyroid function and cardiac involvement. However, there will still be fatal arrhythmias during and after the operation.

摘要：

目的 探讨矽肺伴甲亢患者肺移植术中及术后反复室颤的高危因素，以期术前对其进行有效 的干预，降低手术风险。方法 回顾性分析收治的 1 例矽肺伴甲亢患者肺移植术中及术后反复室颤的临床 资料，并复习相关文献。结果 患者男性，69 岁，因矽肺、呼吸功能衰竭至我院行肺移植术，术前评估诊 断为甲状腺功能亢进，经内分泌科规范诊治，甲亢得到良好控制后接受肺移植手术，但术中及术后出现反 复室颤，经积极抢救成功出院，术后随访 3 个月，患者恢复良好。结论 对于伴甲亢的肺移植患者，术前 一定要积极干预并定期复查甲状腺功能及心脏受累情况，尽管如此，术中及术后仍可出现致死性的心律失常。