Abstract:

Objective To explore the impact of tumor recurrence to long term survival after live transplantation. Methods We retrospectively analyzed the clinical data of 101 cases with liver tumor after liver transplantation between January 2007 and December 2009. The end of follow-up data was December 2012，and the data of dead patients were analyzed. Results The one year survival rate after liver transplantation of malignant tumor patients was about 80%，and the three years survival rate was about 70%. Follow up to December 2012， 35 cases were dead. The first important reason to lead patients dead was tumor recurrence，and the rate was 45.7%. The next reason was hemorrhage，with the rate of 28.6%. Conclusions Tumor recurrence has already been thought to be the significant element impacting the long term survival of liver transplant recipients with primary malignancy. And the clinical emphasis has lied on the prevention of the tumor recurrence and decreasing its rate.

Key words:

Liver transplantation, Tumor recurrence, Long term survival

摘要：

目的 探讨肝移植术后肿瘤复发对于移植患者术后长期生存的影响。方法 回顾性分析解放 军总医院 2007 年 1 月至 2009 年 12 月 101 例因肝脏恶性肿瘤行肝移植术患者的临床资料，随访终点为 2012 年 12 月，并对随访过程中死亡患者的资料进行分析。结果 本院恶性肿瘤患者行肝移植术后 1 年生存率已达到 80% 左右，3 年生存率已达到 70% 左右。随访至 2012 年 12 月，死亡 35 例，其中肿瘤复发是导致患者死亡的首要因素，达到 45.7%，术后出血占第二位，达到 28.6%。结论 肿瘤复发已成为影响恶性肿瘤患者肝移植术后长期存活的主要因素，如何预防和减少肿瘤复发率是今后肝移植工作的重点。

关键词:

肝移植 , 肿瘤复发 , 长期存活