Abstract:

Objective To establish and evaluate a rapid response collaboration system for continuous renal replacement therapy（CRRT）in regional organ donors，assessing its clinical efficacy. Methods The case dataof this study were all from the Second Affiliated Hospital of Guangxi Medical University. This study retrospectively analyzed data from two groups ：the control group consisted of 29 organ donors who received conventional CRRT treatment between September 1，2020 and December 31，2021；the experimental group included 34 organ donors who were treated with the assistance of a CRRT rapid response medical team between January 1，2022，and December 31，2023. The differences in team response time，catheterization time，pipeline installation and pre-charging time，pre-machine preparation time，incidence of adverse events，incidence of complications，and equipment failure rates were compared between the two groups. Results Baseline data between the two groups were comparable （all P ＞ 0.05）. The experimental group demonstrated significantly shorter response times，catheterization times，pipeline installation and pre-charging times，and pre-machine preparation times compared to the control group，with statistically significant differences（all P ＜ 0.05）. No statistically significant differences were observed in the incidence of adverse events，complication rates，or equipment failure rates between the two groups（all P ＞ 0.05）. Conclusion The implementation of a CRRT rapid response team can substantially reduce treatment preparation time，enhance organ maintenance efficiency，and holds significant value for clinical. 

Key words:

Continuousrenal replacement therapy, Quick response team, Organ donor, Management

摘要：

目的 构建区域性器官捐献者连续性肾脏替代治疗（continuous renal replacement therapy，CRRT）快速响应协作体系，并评估其临床效能。 方法 本研究病例资料均来自广西医科大学第二附属医院，以 2020 年 9 月 1 日至 2021 年 12 月 31 日常规 CRRT 治疗的 29 例器官捐献者作为对照组，以 2022 年 1 月1 日至 2023 年 12 月 31 日启动 CRRT 快速响应医护团队后的 34 例器官捐献者作为试验组。比较两组的团队响应时间、置管时间、管路安装及预充时间、上机前准备时间、不良事件发生率、并发症发生率和设备故障次数的差异。 结果 两组基线资料具有可比性（均 P ＞ 0.05）。试验组团队响应时间、置管时间、管路安装及预充时间、上机前准备时间均较对照组明显缩短，差异均有统计学意义（均 P ＜ 0.05）；两组不良事件发生率、并发症发生率和设备故障次数无统计学差异（均 P ＞ 0.05）。 结论 CRRT 快速响应团队可显著缩短治疗准备时间，提升器官维护效率，具有临床推广价值。

关键词: 连续性肾脏替代治疗 , 快速响应团队 , 器官捐献者 , 管理