Abstract:

Objective To summarize the clinical characteristics，diagnosis，treatment and prognosis ofdigestive system malignancy following renal transplantation. Methods The clinical data on fifty-six cases of digestive system malignancy followingrenal transplantationbetween Jan 2000 and July2022 was retrospectively analyzed．Results Among the fifty-sixcases，forty-fourweremalesandtwelve were females.Twoof them had esophageal cancer，ten had gastric carcinoma，twenty-six had liver cancer，three had pancreatic carcinoma，two had tumor of duodenalampulla，and thirteen had intestinal cancer. The diagnosis was made based on the clinical symptoms，laboratory andimaging findings of the patients during follow-up. The patients receivedcomprehensive treatment mainly with surgery. The survival time of patients ranged from one month to eleven years. Conclusion There wasacloserelationshipbetween digestive system tumor and virus infection in renal transplantrecipients. Regular tumor screening after transplantationwas helpful for early diagnosis. According to the characteristics of the tumor，early and appropriate treatment measures should betaken.

Key words:

Kidney transplantation, Digestive system, Malignancy

摘要：

目的 总结肾移植术后消化系统恶性肿瘤的临床特点及诊治经验。方法 回顾性分析中山大学附属第一医院 2000 年 1 月至 2022 年 7 月随诊的 56 例肾移植术后消化系统肿瘤患者的临床资料。结果 56例肾移植术后消化系统肿瘤患者中，男性44例，女性12例，2例为食管癌，10例为胃癌，26例为肝癌，3 例为胰腺癌，2 例为法特壶腹部肿瘤，13 例为肠癌。结合随访期间患者的临床症状、实验室及影像学检查结果进行诊断。患者接受以外科手术为主治疗的综合治疗，存活时间为 1 个月～ 11 年。 结论 肾移植受者术后消化系统肿瘤与病毒感染有密切关系，移植术后定期筛查肿瘤有助于早期诊断，并根据肿瘤特点尽早采取积极合适的治疗措施。

关键词:

肾移植 , 消化系统 , 恶性肿瘤