Abstract:

Objective To investigate the guidance of B cell function testing to the individualized immunosuppressive therapy after liver transplantation. Methods A total number of 24 cases adult liver transplantation recipients who were meeting with the indusion criterias with B-cell function enhancements in Tianjinfirst central hospital from January 2014 to December 2014 were included in this study. IgA，IgG，IgM which could reflect B cell function as well as the alanine aminotransferase（ALT），aspartate aminotransferase（AST），total bilirubin（TB），gamma-glutamyltranspeptidase（GGT），direct bilirubin（DB）and alkaline phosphatase（ALP）were detected before and after using MMF for three months. Results After administrating MMF for 3 months，ALT，AST，TB，GGT decreased significantly（P ＜ 0.05）; DB and ALP also decreased，but there were no statisticallysignificant differences（P ＞ 0.05）. Conclusion MMF administration can improve the liver functions of patients with B-cell function enhancements.