Abstract:

Objective To summarize and analyze the clinical characteristic of HEHE in ChinesepatientsMethods A patent with HEHE underwent liver transplant in Tianjin First Center Hospital，samplesstained by hematoxylin eosin（HE）the morphological characteristics of this cases of hepatic EH were observed．At the same time，detect the expressionof CD31,CD34 protein with En Vision two step immunohistochemical method. According to the clinical manifestations，pathological morphology and the review of the literature. Results The tumor occupied left lateral lobe and right posterior of the liver，Section 5 cm×2 cm×2 cm gray，gray red nodule count，the boundary is not clear，slightly hard matter. Microscopic examination of biopsy，tumor cells were oval or irregular in shape，arranged in cords，abundant cytoplasm is eosinophilic，necrosis and calcification can be seen insome areas，the boundaries of tumor and surrounding liver tissue is unclear. The results of immunohistochemistry fortumor cell CD31，CD34，HMB45，S-100，Vim are positive，Desmin negative，SMA. The patients were followed up for 5 years，alive，but liver，multiple metastases were foung in the liver ans lungs. Conclusion HEHE is a rare low-grade malignant tumor，which is easy misdiagnosed，understand the clinical and pathological characteristic of the tumors can help identify other tumor types confusing.