实用器官移植电子杂志 ›› 2018, Vol. 6 ›› Issue (1): 21-24.

• 论著 • 上一篇    下一篇

心脏死亡供体来源的肾脏受体感染

张景晓 1 ,张玮晔 1, 2   

  • 出版日期:2018-01-20 发布日期:2021-06-24

Cardiac death donor-derived renal infections in renal transplantation recipient

  • Online:2018-01-20 Published:2021-06-24

摘要:

目的 探讨心脏死亡供体单纯泌尿系多重耐药菌感染对肾移植受体的影响。方法 回顾性分 析 2017 年 1 月- 2017 年 8 月天津市第一中心医院的 88 例供者以及与之匹配的 88 例肾移植受者的临床资料, 检测心脏死亡供者血和尿标本中的致病菌,分析受者的感染情况。结果 88 例供者中血培养阴性同时尿培 养阳性的供者 11 例。从尿中分离出的革兰阴性(G- )杆菌占 55.56%。11 例尿培养阳性的供者来源的肾脏受 体中,10 例无感染发生,1 例存在泌尿系感染,但与供者不是同一种细菌。结果中未发现由泌尿系传播的 供体来源的感染。结论 泌尿系存在多重耐药菌感染的供体,经过恰当抗菌药物治疗,可安全的用于供体。

Abstract:

Objective To explore the effects of urinary tract infection by drug-resistant bacteria derived from cardiac death donor on renal allograft recipients. Methods The data of 88 donors and recipients renal transplantations between January 2017 and August 2017 in Tianjin First Center Hospital,were analyzed retrospectively. Pathogens in the blood and urine samples of cardiac death donors were examined. The recipient's infection was analyzed. Results A total number of 11 donors developed urine infections owing to multidrugresistant bacteria without bloodstream infections. The predominant organism isolated from the blood of donors was Gram-positive bacteria(55.56%). A total number of 11 recipients received grafts with positive urine culture, 10 recipients had no infection and 1 recipient had urinary tract infection. However,the pathogen was not the bacteria found in the donor urinary tract. No renal recipients developed donor-derived bacterial infections. Conclusion Our findings supported that renal grafts from DCD donors with urinal infections by multidrug-resistant bacteria can be used on condition of that donors and recipients received appropriate antimicrobial therapy.