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Abstract:

Objective The purpose of this study was to compare the efficacy of autologous inactivatedbone segment and allogeneic bone in reconstruction of bone defect after resection of malignant bone tumors inlimbs. Methods The clinical data of 42 patients with malignant bone tumors of extremities who underwenttumor resection and inactivated autologous or allogenic bone reconstruction from March 2015 to December. 2017 were retrospectively analyzed. Musculoskeletal Tumor Society system（MSTS）and International Society of Limb Salvage（ISOLS）scoring system were used to evaluate and compare the functional and imaging results. Results The follow-up period ranged from 15 to 40 months，with an average of 29 months. At the end of follow-up，the MSTSaverage score of the treated group was 26（17 ～ 31），and the ISOLS average score was 27（23 ～ 32）；The MSTS average score of the treated group was 25（15 ～ 30），and the ISOLS average score was 28（24 ～ 30）. There was nosignificant difference in MSTS and ISOLS scores between the two groups Conclusion After resection of malignantbone tumors in extremities，autologous inactivated bone replantation and allogenic bone reconstruction have the same effect，and there is no significant difference in imaging evaluation.

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