关键词: 儿童肝移植,  , 术后随访策略,  , 生存率,  , 异地随访

Abstract:

Objective To systematically summarize the long-term follow-up strategy for pediatric liver transplantation constructed by Tianjin First Central Hospital，analyze its application effects in ensuring patient survival，improving follow-up adherence，and accurately detecting complications，so as to provide a replicable practical reference for clinical follow-up management after pediatric liver transplantation. Methods A retrospective study was conducted，including 1 967 pediatric liver transplant patients in Tianjin First Central Hospital from 2013 to 2024. A long-term follow-up strategy of“standardized follow-up procedure + multidisciplinary team（MDT）+ information platform”was established. Kaplan-Meier method was used to calculate patient and graft survival rates，and Logistic regression analysis was performed to identify factors influencing follow-up status. Results The1-year，5-year and 10-year patient survival rates were 95.6%、94.1% and 93.8%，respectively，while the 1-year，5-year and 10-year graft survival rates were 94.4%，92.6% and 90.2%，respectively. The regular follow-up rate was91.68%，the pure loss to follow-up rate was 2.07%，and 96 .4% of patients from other provinces received standardized follow-up through the information platform. Multivariate Logistic regression analysis showed that only "postoperativefollow-up time" was an independent risk factor affecting follow-up status（OR＝1.433，95% CI＝1.208～1.700， P＜0.001）. Conclusion The long-term follow-up strategy of "standardized follow-up procedure + MDT + information platform" constructed by our center can effectively ensure long-term patient survival，improve follow-up adherence，and accurately identify late high-risk complications. It is particularly suitable for the clinical situation in China with a high proportion of remote patients，and has important clinical promotion value.

Key words:

"> Pediatric liver transplantation, Postoperative follow-up strategy, Survival rate, Followup adherence in remote patients