实用器官移植电子杂志

实用器官移植电子杂志 ›› 2025, Vol. 13 ›› Issue (5): 443-447.DOI: 10.3969/j.issn.2095-5332.2025.05.011

• 论著 • 上一篇    下一篇

相位角评价胆道闭锁肝移植患儿营养状态的临床研究

王稚晖 1 ，高伟 2 ，谭志军 2 ，郑虹 2    

  1. 1. 天津市儿童医院普外科，天津 300134 ； 2. 天津市第一中心医院肝移植科，天津 300380 ； 3. 天津市第一中心医院营养科，天津 300380
  • 出版日期:2025-09-20 发布日期:2025-09-20
  • 基金资助:
    国家自然科学基金项目（82170672） 

Value of the phase angle from bioelectric impedance analysis in evaluating nutritional status in patients with biliary atresia after pediatric living donor liver transplantation 

Wang Zhihui 1 ，Gao Wei2 ， Tan Zhijun 3 ，Zheng Hong2   

  1. 1. Department of General Surgery，Tianjin Children's Hospital， Tianjin 300134，China ；

    2.Department of Liver Transplantation，Tianjin First Central Hospital， Tianjin 300380， China ；

    3.Nutrition Department，Tianjin First Central Hospital， Tianjin 300380， China.

  • Online:2025-09-20 Published:2025-09-20

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摘要：

目的 探究肝移植患儿相位角（phase angle，PA）及 Z 评分大小与预后的关系。方法 选取2024 年 1 月至 2024 年 6 月于天津市第一中心医院行肝移植术的患儿 61 例，行体格检查和生物电阻抗分析（bioimpedance analysis，BIA）。预后指标包括重症监护室（intensive care unit，ICU）住院天数、机械通气持续时间、总住院天数及术后感染情况。结果 感染组儿童的 PA 值显著低于非感染组（P ＜ 0.05），但两组 Z 评分无显著差异。采用斯皮尔曼相关分析评估 PA、Z 评分与患者预后之间的相关性。PA 与 ICU 和住院时间相关，但与机械通气持续时间无显著相关性（r ＝ -0.229，P ＞ 0.05）。Z 评分与预后无显著相关性。结论 相位角检测能较好地反映肝移植围手术期病者的营养状态，且与患者预后存在相关性，具有较好的应用前景。

关键词:

生物电阻抗分析法 , 相位角 , 营养 , 儿童肝移植

Abstract:

Objective To investigate the relationship between phase angle（PA） and Z-score values andprognosis in pediatric liver transplant patients. Methods A total of 61 pediatric patients who underwent liver transplantation at Tianjin First Central Hospital from January 2024 to June 2024 were selected for physical examination and bioimpedance analysis （BIA）. Outcome measures included intensive care unit （ICU） length of stay， mechanical ventilation duration， total hospital stay， and postoperative infection status. Results Children in the infection group had significantly lower PA values than those in the non-infection group （P ＜ 0.05）， but there was no significant difference in Z-scores between the two groups. Spearman's correlation analysis was used to assess the correlation between PA， Z-score， and patient outcomes. PA was associated with ICU and hospitalization duration but not with mechanical ventilation duration （r ＝ -0.229，P ＞ 0.05）. Z-score was not significantly associated with prognosis. Conclusion Phase angle measurement can effectively reflect the nutritional status of pediatric patients undergoing liver transplantation and is associated with patient prognosis， demonstrating promising application potential. 

Key words:

Bioelectric impedance analysis； , Phase angle； , Nutrition； , Pediatric liver transplantation

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