Abstract:

Objective To evaluate the left and right ventricular function by Tei index assessed by pulsed wave doppler imaging in patients with liver cirrhosis before orthotopic liver transplantation（OLT）. Methods InTianjin First Center Hospital，between May 2014 and September 2014，we choose 38 patients with liver cirrhosisbefore OLT as cirrhosis group，27 healthy controls as control group and let them underwent color doppler echocardiography. The peak filling velocity of E wave and A wave，ejection fraction（EF）of left and right ventricular were measured，E/A and Tei index were calculated and compared. Results There was no significant difference in left ventricular end diastolic diameter（LVDd）、left atrial end systolic diameter（LADs）、right ventricularend diastolic diameter（RVDd）、right atrial end systolic diameter（RADs）、EF of left and right ventricular andE/A（all P ＞ 0.05）between cirrhosis group and control group. Tei indices of left and right ventricle in cirrhosis group（0.56±0.12，0.46±0.10）were higher than those of normal control group（0.41±0.07，0.37±0.06）（both P ＜ 0.05）. Conclusion Tei index assessed by pulsed wave Doppler imaging is a good way to evaluate the global heart function. It can be used to evaluate the patients with liver cirrhosis before OLT and provide guidance for clinical treatment.

摘要：

目的 探讨脉冲多普勒 Tei 指数评价原位肝移植（OLT）术前肝硬化患者的左心及右心功能的价值。方法 选择 2014 年 5 月至 9 月天津市第一中心医院收治的 38 例 OLT 术前肝硬化患者作为肝硬化组，27 例年龄相匹配的正常人作为正常对照组，两组均行彩色多普勒超声心动图检查，测量左心室射血分数（LVEF）、右心室射血分数（RVEF）、二尖瓣及三尖瓣舒张早期血流峰值（E 峰）、舒张晚期血流峰值（A 峰），计算并比较 E/A 比值及 Tei 指数。结果 OLT 术前的肝硬化患者左心室舒张末期内径（LVDd）、左心房收缩末期内径（LADs）、右心室舒张末期内径（RADs）、右心房收缩末期内径（RADd）、LVEF、RVEF、E/A 比值与正常对照组比较差异均无统计学意义（均 P ＞ 0.05）；而肝硬化患者左心室 Tei 指数（0.56±0.12）、右心室的 Tei 指数（0.46±0.10）均高于正常对照组（分别为 0.41±0.07、0.37±0.06），两组比较差异均有统计学意义（均 P ＜ 0.05）。结论 脉冲多普勒 Tei 指数是评估心功能的一种简便易行的可靠方法，可用于评价 OLT 术前肝硬化患者的心脏整体收缩和舒张功能，为临床治疗提供指导。