Abstract:

Objective Evaluation of the efficacy and safety of Percutaneous portal vein puncture andonyx glue for the closure of transhepatic puncture tracts in islet cell transplantation patients. Methods Between June 2015 and June 2016, 5 percutaneous transhepatic accesses were closed using percutaneous Onyx glue in islet cell transplantation patients under fluoroscopy. To observation the complications of bleeding and infection，Postoperatively. Results In islet cell transplantation patients， percutaneous portal vein puncture success rate was 100%. The portal venous pressure was 6 -15 mmHg〔（9.40±3.91）mmHg，1mmHg ＝ 0.133 kPa〕before islet cell transplantation. The portal venous pressure was 6-15 mmHg〔（10.20±4.44）mmHg〕 after transplantation. The portal vein pressure showed no statistically significant differences before and after transplantation（P ＞ 0.05）. Intraoperative and postoperative follow-up showed no treatment-related complication. Conclusion Percutaneous portal vein puncture and onyx glue application are effective and safe technique for the closure of transhepatic accesses in islet cell transplantation patients.

摘要：

目的 探讨透视下经皮门静脉穿刺与 Onyx 胶封堵穿刺入路在胰岛细胞移植术中的安全性和有效性。方法 收集天津市第一中心医院 2015 年 6 月 -2016 年 6 月进行胰岛细胞移植 5 例患者的临床资料，患者均为透视下经皮经肝门静脉穿刺、门静脉内胰岛细胞移植，术后均应用 Onyx 胶封堵门静脉穿刺道，术后观察有无出血及感染并发症发生。结果 5 例患者均门静脉穿刺成功，技术成功率为 100%。胰岛细胞移植前后门静脉压力为6～15 mmHg（1 mmHg＝0.133 kPa），平均（9.40±3.91）mmHg，移植后门静脉压力为6～15 mmHg，平均（10.20±4.44）mmHg，胰岛细胞移植前后门静脉压力差异无统计学意义（P ＞ 0.05）。 术中及术后随访观察无介入治疗相关并发症发生。结论 透视下经皮门静脉穿刺与 Onyx 胶封堵穿刺入路在胰岛细胞移植术中安全、有效。