Abstract:

Objective To investigate the nocturia and its impact on the quality of life in the non-eldlymale patients after successful renal transplantation and to explore the related risk factors and causes which led tonocturia. Methods We designed a patient-completed questionnaire according to the characteristics of clinicalrecords，international prostate symptom score（IPSS）and quality of life score. We distributed the questionnairesand instructed them to fill in the meetingspot of kidney transplant friends. Results A total of 182 questionnaires were distributed and 120 were collected，only 90 cases meet the requirements of the study. The prevalence of nocturia（awakening at night twice or more to void）were 61 cases（67.8％）. Seventy-six cases（84.4％）of all patients were satisfied with the quality of life after renal transplantation. There was no statistically correlation betweenurine output before transplantation（24 hours），the total time of hemodialysis before operation，24 hours fluid intake now，the total time after operation and nocturia（all P ＞ 0.05）. Conclusions Nocturia was very prevalent in the non-eldly male patients after successful renal transplantation. This research demonstrated that nocturia may be caused by many risk factors interactions and did not bring an obvious adverse impact on the quality of life after successfulrenal transplantation．

Key words:  , Renal transplantation； Nocturnal polyuria ； Nocturia ； Lower urinary tract symptoms

摘要：

目的 调查成功肾移植术后非老年男性受者的夜尿情况及生活质量，并探讨引起夜尿症的相关危险因素及原因。方法 采用自我完成的问卷调查，内容包括肾移植手术前后主要临床记录特征、国际前列腺症状评分表（IPSS）以及生活质量评分表。在本院举办肾友会时，现场发放调查问卷并指导填写。结果 调查问卷共发出 182 份，回收 120 份，90 份符合此次研究的条件。90 例患者中，61 例（67.8％）出 现夜间排尿次数≥ 2 次，76 例（84.4％）对目前的生活质量表示满意。肾移植术前尿量、术前总透析时间、目前 24 小时液体摄入量、肾移植术后时间与夜尿次数均无统计学相关性（均 P ＞ 0.05）。结论 夜尿症是 成功肾移植术后非老年男性受者中普遍存在的现象。本次研究表明夜尿症可能是由多种危险因素相互作用 的结果，而且此类症状并未对该类人群的生活质量产生重大的不良影响。

关键词: 肾移植 , 夜尿增多 , 夜尿症 , 下尿路症状