Abstract:

Objective To explore the effectiveness of the omentum islet transplantationprocedure. Methods Two patients with type 1 diabetes mellitus（T1DM）were transplanted with islet isolatedby laparoscopic approach，resorbable plasma-thrombin as the biologic scaffold in this procedure. Results Tworecipients recovered smoothly after islet transplantation，the level of blood glucose was stable，the level of C- peptidewas significantly higher than pre-transplantation，and the hemoglobin A1c level was decreased 2 month after islet transplantation. Conclusions Islet transplantation is currently one of the promising methods of treatment of T1DM, we transplanted islets to the greater omentum, and the result showed that the procedure of omentum biological scaffold

islet transplantation for T1DM patients provided a feasible technique route.