Abstract:

Objective To summarize the application of early exercise combined with respiratory rehabilitation in two cases of heart-kidney transplantation，and to provide clinical practice theory for patients withheart-kidney transplantation. Methods From November 2020 to March 2021，two patients who underwentearly exercise combined with respiratory rehabilitation after heart-kidney transplantation in transplantationmedicine Center，the Second Affiliated Hospital of Guangxi Medical University were selected. The clinical and follow-up data of the patients were collected and analyzed，and the anxiety and depression score，muscle strength score，nutrition score，thrombus score，blood gas analysis index and postoperative follow-up pulmonaryinfection index were analyzed. Results The scores of anxiety and depression were significantly decreased，the scores of muscle strength， nutrition and thrombosis were significantly improved，PaO2 （arterial partial pressure of oxygen），SaO2 （arterial oxygen saturation）were increased and PaCO2 （partial pressure of carbon dioxide）was decreased in two patients who underwent early exercise combined with respiratory rehabilitation after heart-kidney transplantation. No pulmonary infection occurred during two years of follow-up. Conclusion Early exercise combined with respiratory rehabilitation can provide theoretical guidance and improve the psychological state，blood gas analysis index and exercise endurance of patients with heart-kidney combined transplantation. 

Key words:

Combined transplantation of heart and kidney, Early exercise, Respiratory rehabilitation

摘要：

目的 总结早期运动联合呼吸康复在心肾联合移植中的应用 2 例，为心肾联合移植受者行早期运动联合呼吸康复提供临床实践理论。 方法 选取 2020 年 11 月至 2021 年 3 月在广西医科大学第二附属医院移植医学中心行心肾联合移植后进行早期运动联合呼吸康复受者临床资料，采用病例回顾性分析，收集受者临床及随访资料，分析受者焦虑抑郁评分、肌力评分、营养评分、血栓评分、血气分析指标及术后随访肺部感染指标。 结果 2 例心肾联合移植行早期运动联合呼吸康复受者，术后焦虑及抑郁评分明显下降，术后肌力、营养及血栓评分明显改善，受者动脉血氧分压（arterial partial pressure of oxygen，PaO2）、 血氧饱和度（arterial oxygen saturation，SaO2）升高，动脉血二氧化碳分压（partial pressure of carbon dioxide，PaCO2）降低，随访 2 年未出现肺部感染。 结论 早期运动联合呼吸康复可改善心肾联合受者心理状态，改善受者血气分析指标，提高受者运动耐力，为心肾联合移植实施早期运动联合呼吸康复提供临床实践理论指导。

关键词:

心肾联合移植 , 早期运动 , 呼吸康复