Report of 13 cases of organ transplantation using donation after cardiac death donors

Practical Journal of Organ Transplantation(Electronic Version) ›› 2013, Vol. 1 ›› Issue (1): 17-21.

Report of 13 cases of organ transplantation using donation after cardiac death donors

ZHANG Wei-jie，CHEN Zhi-shui，WEI Lai，MING Chang-sheng，ZHOU Ping，CHEN Gang，ZENG Fan-jun， CHANG Sheng，CHEN Dong，DU Dun-feng，GUO Hui，CHEN Xiao-ping.

Institute of Organ Transplantation，Tongji Hospital，Tongji Medical College，Huazhong University of Science & Technology，Wuhan 430030，Hubei，China

Online:2013-01-20 Published:2021-04-15

心脏死亡器官捐献移植 13 例报告

张伟杰，陈知水，魏来，明长生，周平，陈刚，曾凡军，昌盛，陈栋，杜敦峰，郭晖，陈孝平

华中科技大学同济医学院附属同济医院器官移植研究所，教育部 / 卫生部器官移植重点实验室，湖北武汉 430030

基金资助:
国家高技术研究发展计划（863）项目（2012AA021010）

Abstract

Abstract:

Objective To investigate the feasibility and precautions of donation after cardiac death（DCD），clinical data of organtransplantations using DCD donors were analyzed. Methods We retrospectively reviewed the clinical data of organ transplantations using DCD donors in Tongji Hospital of Tongji Medical College of Huazhong University of Science & Technology from March 2010 to October 2012. Results There were totally 13 recipients in this study，including 8 kidney transplants and 5 liver transplants，2 renal grafts were resected because of renal graft artery rupture and acute antibody-mediated rejection respectively，1 kidney transplant recipients died of cerebrovascular accident，1 liver transplant recipient died of hepatic artery rupture. Totally 1-year graft / recipient survival was 69.2% and 84.6% respectively. Conclusion Donor source can be expanded with DCD donors，theoccurrence of complications should be paid attention to and the effects of DCD transplantation should be improved.

Key words: Donation after cardiac death, Liver transplant, Kidney transplan

摘要：

目的通过观察心脏死亡器官捐献（Donation after Cardiac Death，DCD）移植器官的临床结果，探讨 DCD 移植的可行性和注意事项。方法对华中科技大学同济医学院附属同济医院 2010 年 3 月至2012 年 10 月期间施行的 DCD 移植器官的临床资料进行回顾性总结。结果共有 13 例受者纳入研究，包括8 例肾移植和 5 例肝移植，手术顺利。肾移植病例中术后分别因移植肾动脉破裂、急性抗体介导的排斥反应（AAMR）而切除移植肾 2 例，因脑血管意外死亡 1 例。肝移植病例中因肝动脉出血死亡 1 例。总体 1 年移植物 / 人存活率分别为 69.2% 和 84.6%。结论使用 DCD 捐献器官可以扩大供体来源，缓解器官短缺困难，但应注意并发症发生，提高移植效果。

关键词:

心脏死亡器官捐献 , 肝移植 , 肾移植

ZHANG Wei-jie, CHEN Zhi-shui, WEI Lai, MING Chang-sheng, ZHOU Ping, CHEN Gang, ZENG Fan-jun, CHANG Sheng, CHEN Dong, DU Dun-feng, GUO Hui, CHEN Xiao-ping..

Report of 13 cases of organ transplantation using donation after cardiac death donors

[J]. Practical Journal of Organ Transplantation(Electronic Version), 2013, 1(1): 17-21.

张伟杰, 陈知水, 魏来, 明长生, 周平, 陈刚, 曾凡军, 昌盛, 陈栋, 杜敦峰, 郭晖, 陈孝平.

心脏死亡器官捐献移植 13 例报告

[J]. 实用器官移植电子杂志, 2013, 1(1): 17-21.

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