Abstract:

Objective To evaluate the feasibility, safety of transjugular liver biopsy (TJLB) in patients with liver transplantation (LT) . Methods From December 2013 to January 2014, there were three cases with coagulation impairment or ascites after LT. TJLB was performed in these 3 patients. The results were monitored by clinical follow-up, liver biopsy and complications. Results Technical success was achieved in all TJLB without complications. 1, 2, 3 passages were performed in the procedures, respectively. TJLB were performed within 2 weeks after LT, and 2 cases were diagnosed as acute rejections and 1 as hepatitis recurrence and biliary tract complication. Conclusion Our experience with TJLB, using an automated core needle biopsy, has shown this technique to be a feasible and safe procedure in this small series of patients who underwent LT with severe ascites or coagulation impairment.

Key words:

Liver transplantation , Transjugular liver biopsy, Ascites , Coagulation impairment

摘要： 目的 探讨经颈静脉肝活检（TJLB ）技术在肝移植术后合并凝血功能障碍和腹腔积液患者 应用的安全性和可行性。方法 回顾性分析2013年12月至2014年1月肝移植术后合并腹腔积液或凝血 功能障碍3例患者资料，3例患者均行TJLB,对患者临床资料、肝活检及术后并发症等情况进行总结。 结果 所有TJLB患者均取得了技术成功且无相关并发症。3例患者分别取1、2、3段活检组织。所有患 者均在肝移植术后2周内进行TJLB, 2例诊断为急性排斥反应，1例诊断为肝炎复发、胆道并发症。结 论TJLB技术在肝移植术后合并凝血功能障碍和腹腔积液患者中应用是安全可行的。

关键词:

肝移植, 经颈静脉肝活检, 腹腔积液, 凝血功能障碍